indiegame.fan
Nope Nope Nurses Melee header art

Nope Nope Nurses Melee

The unbelievable spinoff off Sakusei Byoutou! You might not believe it, but it's now a 2D fighting game! It's kill or be killed, and either way you're getting sucked dry!

Steam Page
Publisher
Release
February 21, 2024
2 years and 163 days ago
Steam Reviews
Mostly Positive18 reviews77.8%

Does this feel indie?

Vote based on whether this game feels indie to you. You can change your vote at any time. Results earn an IGF score after 10 accepted votes.
No votes yet
Vote on More Games
Game contextLatest: IGF Team
ContextThe evidence factors used to assess whether this game belongs on IndieGame.Fan.Status
Notes
Latest Contributor: IGF TeamEdit notes
Updated: Jul 14, 2026Developer scaleThe operating scale of the game's developer.
Updated: Jul 14, 2026Publisher scaleThe operating scale of the game's publisher.
JAST meets the large-publisher game and partner thresholds.
Search Google: Is Nope Nope Nurses Melee self-published or published by JAST?Publisher statusHow the game's publishing relationship is classified.
Search Google: How is Nope Nope Nurses Melee and JAST funded?FundingThe known source of funding behind the game.
Search Google: Who controls the creative direction and IP for Nope Nope Nurses Melee and Sakuken Games (SAKUSEI RESEARCH LAB x YANO KAKUTOU)?Creative controlWho appears to retain creative control of the game.
Updated: Jul 14, 2026Release statusWhether and how the game has been released.
JAST is listed as a separate publisher for this release.

Media

10 items

About the Game

The unbelievable spinoff off Sakusei Byoutou! You might not believe it, but it's now a 2D fighting game! It's kill or be killed, and either way you're getting sucked dry!

An entirely original story in the universe of Sakusei Byoutou, brought to you in the form of a 2D fighting game!
We've teamed up with Yano Kakuto, the game developer headed by Yano Tomoyuki of NO Motion, to bring you this fresh new spin on things!
Relive the good old days of the small screen as your favorite nurses duke it out in a 640x480 window!

In the story mode, you will play as Tachibana, defeating other nasty nurses to advance the plot.
All characters are playable in VS mode. Local two-player battles are available.
※Online battles are not supported.

Sakusei Fighters features a wide range of original systems to spice things up, such as Medical Combos, Special Overdrives, and the Sperm Stock system.
Make no mistake, this game is more than just a silly joke - it's the real deal.

An Easy mode is available for players new to fighting games or who wish to focus on the story.
It will let you experience all the thrills of battle with a simple input scheme!

Story
It all begins with a mysterious pot of coffee left in the nurses' station.
After drinking it, the nurses all become terribly aggressive, irritated by anything and everything.
Our protagonist, Tachibana, is no exception. While she recognizes that something is wrong, she cannot resist the call of battle!

Meanwhile, the nurses she defeats find themselves still unable to quell their arousal and turn to Yamada to satiate their desires!
Just who is behind all of this madness? Find out for yourself!

Read Before Playing

This game was made in 2D Fighter Maker 2nd, a program released in 2000. As such, the following issues have been identified:

* In order to boot the game, you must install and enable DirectPlay.
* Fullscreen mode is not supported by some video cards.
* Controller support is not guaranteed. Please use an external tool to map key inputs if necessary.
* The system options menu was unable to be translated within the game itself. Please refer to the manual for a translation of this menu.
* Online play is not supported.
Note 1: This game was made using 2D Fighter Maker 2nd.
Note 2: Some graphical and music assets were created using AI.