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Immunica

Become the immune system. Hover to kill. Weapons fire automatically. Manage your research lab, hire scientists, and develop a vaccine while fighting off endless pathogen hordes.

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Release
March 29, 2026
125 days ago
Steam Reviews
Mostly Positive48 reviews75.0%

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About the Game

In Immunica, YOU are the immune system. Pathogens are flooding in. Your health is dropping. Every second counts.

Control the immune system from within. No clicking required. Just move, position, and watch the chaos unfold as your weapons automatically tear through waves of invaders.

ACTIVE SURVIVAL + IDLE PROGRESSION

Hover over enemies to deal damage. Your cursor is your primary weapon. Meanwhile, missiles lock on, beams fire, drones orbit, and burst pulses detonate around you. Focus on positioning while your arsenal handles the rest.

4 WEAPON SYSTEMS

  • Burst - AOE pulse centered on your cursor

  • Missiles - Homing projectiles that hunt down targets

  • Beam - High-damage laser for focused destruction

  • Drones - Orbiting allies that intercept incoming threats

FEVER MODE

Chain kills to build your Fever meter. When it fills, unleash devastating power: up to +500% damage across 5 escalating tiers. The more you kill, the stronger you become.

40+ PATHOGEN SPECIES

Face 8 pathogen types across multiple tiers. From tiny Prions to massive Helminths, each species brings unique behavior patterns. Every pathogen has 3 evolution levels: Normal, Mutant, and Alpha. Higher tiers mean deadlier enemies and greater rewards.

RESEARCH LAB

Between breaches, manage your own research laboratory. Collect pathogen samples from combat and assign them to your scientists. Hire interns, technicians, researchers, and senior scientists. Each has different processing speeds, efficiency rates, and capabilities. Watch your team analyze samples even while you are away. Progress continues offline for up to 8 hours.

Your goal: accumulate enough Vaccine Data to complete the cure.

DEEP UPGRADE SYSTEM

Over 200 upgrades across multiple categories. Improve your cursor damage, fire rate, and critical chance. Unlock weapon systems and enhance their power. Strengthen your core health and damage resistance. Every protein spent makes you permanently stronger.

BREACH MODIFIERS

Each run randomly selects 1-3 modifiers from 30 possibilities:

  • Buffs - Advantages that boost your power

  • Nerfs - Increased difficulty with bonus protein rewards

  • Weird - Strange effects that completely change how the game plays

KEY FEATURES

  • Satisfying incremental progression that persists across runs

  • Active cursor gameplay combined with automated weapons

  • Idle lab management with offline progression

  • 40+ pathogen species with 3 evolution levels each

  • 30 breach modifiers for endless variety

  • Hidden synergies to discover through gameplay

  • Work toward a final goal: completing the vaccine