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Genome Guardian 2

COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!

Developer
Alpherior
Publisher
Alpherior
Release
October 11, 2026
19 days ago
Steam Reviews
Very Positive524 reviews94.3%
...INDIE
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Game contextLatest: IGF Team
ContextThe evidence factors used to assess whether this game belongs on IndieGame.Fan.Status
Notes
Latest Contributor: IGF TeamEdit notes
Updated: Jul 10, 2026Developer scaleThe operating scale of the game's developer.
Updated: Jul 10, 2026Publisher scaleThe operating scale of the game's publisher.
Updated: Jul 10, 2026Publisher statusHow the game's publishing relationship is classified.
Search Google: How is Genome Guardian 2 and Alpherior funded?FundingThe known source of funding behind the game.
Search Google: Who controls the creative direction and IP for Genome Guardian 2 and Alpherior?Creative controlWho appears to retain creative control of the game.
Updated: Jul 10, 2026Release statusWhether and how the game has been released.

Media

21 items

About the Game

Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors.

Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.

Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves!

Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.

  • Easily recreate your favourite turrets from the first game…or combine em' all into one frankenstein monstrosity

  • Save/Load 24 loadouts

  • Paint & Pattern customization

Pair DNA nucleotides A (rapidfire), C (precision), G (spread), T (explosive) to discover 70 hybrid bioweapons!

  • Shotgun + Bomb mix explosives with spread for Blast Shotgun!

  • SMG + Pistol make an accurate, fast-firing Scout Rifle!

  • Blast Shotgun + Scout Rifle = something a whole lot crazier!

  • 20-minute runs you can save & resume at any time + improved Endless Mode

  • Complete side objectives during runs for extra cash

  • Mine mineral deposits for resources

  • Trigger powerful Gadget active abilities

  • Test discovered weapons in the Database

  • 100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode

  • Auto aim/fire toggles

  • Localization in 10 languages

  • Full rebinding for keyboard & gamepad

  • 400% better performance/framerate on high & low-end PCs

  • Accessibility for colourblindness, motion sickness & arachnophobia

  • 100 Steam achievements

  • Cloud Save

  • Plays great on Steam Deck!

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