Gene Jackpot
A roguelike deckbuilder where you gamble with your own genes. Every card played mutates your body. Every defeat triggers unpredictable mutations. Become a different monster every run. Losing has never been this fun.
Developer
Publisher
Release
April 28, 2026
96 days ago
Steam Reviews
1 user reviews1 reviews100.0%
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Game contextLatest: IGF Team
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Media
8 itemsAbout the Game
[h1]Your Genes Are Your Cards[/h1]
Gene Jackpot is a roguelike deckbuilder where you gamble with your own genetic code.
You are G-00, a gene experiment. To escape a biotech corporation's underground lab, you must weaponize your own DNA. Play a Strength gene and your arm grows massive. Play a Toxin gene and your skin discolors. Play an Electric gene and your nervous system overloads.
Defeat doesn't end your run. Every time you fall, unpredictable contamination mutations reshape your body. Mutations aren't always bad — they can trigger bizarre synergies. Losing on purpose is a valid strategy. But get knocked out three times, and it's truly over.
"The Genesis Project" — a secret project to break the limits of human genetics. Among hundreds of failed experiments, G-00 is the only stable subject. As you awaken and attempt to escape, the lab's secrets, the truth about the experiments, and the existence of "the Original" unfold with every run.
If you love Slay the Spire's deckbuilding, Balatro's synergy explosions, Darkest Dungeon's darkness, and Hades' meta-progression — Gene Jackpot is a gamble with your very DNA.
Gene Jackpot is a roguelike deckbuilder where you gamble with your own genetic code.
You are G-00, a gene experiment. To escape a biotech corporation's underground lab, you must weaponize your own DNA. Play a Strength gene and your arm grows massive. Play a Toxin gene and your skin discolors. Play an Electric gene and your nervous system overloads.
Losing Is Fun
Defeat doesn't end your run. Every time you fall, unpredictable contamination mutations reshape your body. Mutations aren't always bad — they can trigger bizarre synergies. Losing on purpose is a valid strategy. But get knocked out three times, and it's truly over.
Mutation System
- Real-time Mutation — Your character's appearance changes with every card combination
- Mutation Gauge — Reach 100% to evolve into a perfect form... or collapse
- 7 Attribute Synergies — Combine Toxin, Fluid, Strength, Bone, Psy, Electric, and Parasite genes
- A Different Monster Every Run — No two builds are ever the same
Key Features
- Roguelike Deckbuilding — Fresh card combinations and mutation paths every run
- Biopunk World — A gene experiment's escape story. Each run reveals more of the truth
- 4 Playable Characters — Each with unique starter decks and mutation traits
- Research Hub — Between runs: NPC dialogue, upgrades, and codex
- Ascender System — Increasing difficulty tiers as you clear runs
- Procedural Coding Art — All visuals generated entirely by code. A unique art style like no other
Story
"The Genesis Project" — a secret project to break the limits of human genetics. Among hundreds of failed experiments, G-00 is the only stable subject. As you awaken and attempt to escape, the lab's secrets, the truth about the experiments, and the existence of "the Original" unfold with every run.
If You Love These Games
If you love Slay the Spire's deckbuilding, Balatro's synergy explosions, Darkest Dungeon's darkness, and Hades' meta-progression — Gene Jackpot is a gamble with your very DNA.
