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Auto Immune

A virus is attacking your cells, and its up to you to defend them! Buy and combine cells to assemble your immune response. Discover powerful synergies to overcome a constantly evolving enemy in this physics-based auto battler. Can you achieve IMMUNITY?

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Latest Contributor: IGF TeamEdit notes
Updated: Jul 10, 2026Developer scaleThe operating scale of the game's developer.
Updated: Jul 10, 2026Publisher scaleThe operating scale of the game's publisher.
Updated: Jul 10, 2026Publisher statusHow the game's publishing relationship is classified.
Search Google: How is Auto Immune and Distant Signal Games funded?FundingThe known source of funding behind the game.
Search Google: Who controls the creative direction and IP for Auto Immune and Distant Signal Games?Creative controlWho appears to retain creative control of the game.
Updated: Jul 10, 2026Release statusWhether and how the game has been released.

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About the Game

A virus is attacking your cells, and its up to you to defend them! Buy and combine cells to assemble your immune response. Discover powerful synergies to overcome a constantly evolving enemy in this physics-based auto battler. Build an ironclad immune defense in 10 turns or perish.

Create the ultimate immune response


Create the ultimate immune response: Combine immune cells in interesting ways to overcome incoming pathogens. Merging the same immune cells together will strengthen them and can unlock higher tier immune cells to experiment with. Chaining different cells together can reveal powerful synergies.

Adapt or die:


Adapt or die: Viruses will multiply each turn and become an even bigger threat! You’ll adapt to the current situation and form the best defense given limited resources.

Outlive or Outlast


In single player mode, the objective of the game is to make it to turn 12. In asynchronous multiplayer mode you win by outlasting the replays from other player's games and gain rank.

If you made this far...

You made it past the fold! You deserve a reward. Here are a few tips to make sure you can get the most out of the game as quickly as possible!

Basics Tips:
  • You CANNOT destroy the Infected cells that spawn viruses. Focus on defending against the viruses.
  • You can rotate cells if you grab and drag the black arrow that appears after placing them
  • Cells cost money ("Carbs")! You start with 4 and gain one every turn. You lose any money you don't spend at the end of your turn.
  • Everything resets after every Infection round, unless it says otherwise. Damage is not persistent between rounds!

Intermediate Tips:
  • Try to spend all your money each turn! Its use it or lose it unless you have a cell that works on unspent money.
  • You can combine any two cells with the same name. Combining two has double the health. But combine 3 and it becomes
    an elite cell (which is usually as strong as 2 non-elites) and allows to choose a Reward cell.
  • Reward cells are some of the strongest in the game! So don't miss out on combining as this is the only way to get them.
  • You CAN move your Blood Cells. This can give you a lot more space to work with!
  • Viruses can open attack lanes from any direction except directly down.
  • But they will only open a maximum of 3 lanes, including the first one which always attacks from the right.