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Against the Gradient

A microscopic world is in need of your help! Add transporters to membranes to move molecules and ions into and out of cells. Your goal is to reach specific concentrations.

Steam Page
Release
July 10, 2017
9 years and 24 days ago
Steam Reviews
3 user reviews3 reviews100.0%

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Updated: Jul 11, 2026Developer scaleThe operating scale of the game's developer.
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Search Google: How is Against the Gradient and Cogent Education funded?FundingThe known source of funding behind the game.
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About the Game

A microscopic world is in need of your help! Add transporters to membranes to move molecules and ions into and out of cells. Your goal is to reach specific concentrations.

Over 20 unique puzzles will help you master the principles of cellular transport. Use channels, co-transporters, and antiporters to master facilitated diffusion and active transport.

Think you understand how transporters diffuse molecules and ions across the membrane? Try making your own puzzles with the built in level editor!

Features:
  • Over 20 puzzles ranging from a gentle introduction to challenging mind benders.
  • Speed up and slow down time to play at your own pace.
  • 16 transporters including real proteins found in your body and imaginative nano-robots.
  • Puzzle mechanics based on real biological principles of cellular transport.
  • Built-in level editor lets you take control and make your own levels to challenge your friends!